Our thongs run small, so please size up! Also remember that sometimes your butt size doesn't align with the rest of your clothing size. I usually wear an XS for pants and a small for undies, but I wear a medium for these guys. Here's a chart:
 
 US size UK size Buttercup size
000 - 00 0 - 2 XS
0 - 2 4 - 6 S
2 - 4 6 - 8 M
6 - 8 8 - 10 L
10 12 XL